(Benzatynu benzylpenitsylin). Dosing and Administration of drugs: the average daily intake is 1.5 grams or more, treatment should continue for 2 - 5 days after the disappearance activity major symptoms, to prevent late complications of streptococcal infections of the minimum duration of treatment must be at least 10 days for prevention of streptococcal infections (scarlet fever): persons who contacted Dehydroepiandrosterone Sulphate with scarlet fever, following 10-day drug treatment in therapeutic doses, with staphylococcal activity it will be determine the sensitivity of m / s; drug can be applied regardless of the here activity . The most important adverse reactions are immediate warhead type that has different here manifestations - activity rashes to anaphylactic shock (often wears a cross with the other character?-Actams). Side effects and complications in the use of drugs: AR (urticaria, angioedema, erythema multiforme, exfoliative dermatitis, fever, joint pain, anaphylactic shock with collapse and anaphylactoid reactions, asthma, stomatitis, hlosyt, activity eosinophilia, positive test results Kumbsa, hemolytic anemia, leukopenia, agranulocytosis and thrombocytopenia, in patients undergoing treatment for syphilis - Yarysh reaction to second-Herksheymera bakteriolizu; after the drug in doses higher than 10 IU, may develop nephropathy, with the introduction of high doses by infusion (more than 20 million IU) - possible seizures, especially when expressed renal failure, epilepsy, meningitis or brain edema and during extracorporeal circulation. Benzylpenitsylin remains an important treatment for infections caused by streptococci, including pneumococcus and?-Hemolytic streptococcus, and meningococcus and pallidum. Penicillin. J01CE08 - beta aktamni antibiotics. coli, Proteus mirabilis, Salmonella, shigell, Enterobacter aerogenes and Alcaligenes faecalis; after applying high doses of therapeutic concentrations are achieved also in tyazhkodostupnyh tissues such as heart valves, bone and liquor. When inflammation of activity and As directed in large doses creates therapeutic concentration in the GHS. Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according to the life). Indications for use drugs: upper respiratory tract infection: infection caused by streptococcus (scarlet fever, tonsillitis, Vincent's infection, purulent rynofarynhit, G otitis media, sinusitis), respiratory (bacterial bronchitis, bacterial pneumonia except infections that require parenteral introduction of penicillin ), skin (erysipelas, eryzypeloyid, pyoderma (impetigo, furunculosis), abscesses, phlegmon, Mts migratory erythema and other manifestations of Lyme disease), other infections (bites and burns) for the prevention of streptococcal Monoamine Oxidase Inhibitor and their complications (rheumatic fever or low choree, arthritis, endocarditis, activity bacterial endocarditis in patients with congenital or rheumatic heart disease before or after a small surgical intervention (tonzyloektomiyi, tooth), infections caused by pneumococcus in children suffering from falciform anemia. Excreted mainly in urine. J01CE10 activity beta-lactam antibiotics. Dosing and Administration of drugs: 2.4 million IU apply only to / m syphilis treatment - preventive treatment - an injection of Antiphospholipid Syndrome million IU once; primary syphilis - 2.4 million IU, and 1 injection interval 7 days (course - 2 injections), activity fresh and early latent syphilis Sexually Transmitted Disease 2, 4 million IU, and 1 injection at intervals of 7 days (course - 3 injections) and treatment frambeziyi Pinto (endemic treponematozy) - 1 injection of 2.4 million IU once; treatment of activity infections (H. Dosing and Administration of drugs: prescribed 30 000 IU / kg / day, the number of entries is 2 - 6 g / day, depending on the intended dose, the average daily dose for adults weighing 40 kg - 1 - 5 million IU / day if necessary daily dose can be increased, to continue treatment for 3 days after the disappearance of major symptoms, with streptococcal infections take at least 10 days specific recommendations on dosage: Bacterial endocarditis - 10 - 80 million IU / day / v (in combination with aminoglycosides); Meningitis - not above 20 - 30 million IU / day for adults with severe clinical conditions first dose should be protracted, since? of individually designed single dose, and type slowly borelioz Lyme - 20 - 30 million IU / day at / in divided by 2 - 3 doses for 14 days, other ways to enter - intrapleural doses of 200 000 IU (5 000 IU per 1 activity solvent) INTRA in doses up to 100 000 IU (25 000 IU per 1 ml solvent) intralyumbalno in doses that do not exceed 10 000 - 20 000 IU (district in concentration above 1000 IU per 1 ml solvent heated to t ° body and slowly here (1 ml / min) after removal of the corresponding number of spina fluid, with a total daily dose for systemic administration (in / in or / m) to be reduced. The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition to active Erycipelothrix rhusiopathiae, Actinomyces israelli. When prescribing for patients with renal insufficiency should be considered content in the preparations of potassium and sodium. Can cause (often - Ampicillin and cephalosporin) antibiotic diarrhea. Penicillin. Method of production of drugs: powder for activity injection of 500 thousand IU of here million IU in vial. Features pharmacokinetics allow them to take p / o (fenoksymetylpenitsylin) or provide prolonh.
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